Technologies for Biological Space Exploration (T4BSE)

Study Objective

Implement a biological systems focused technology definition, development, and applications strategy to enable cross-species comparative biological research on a variety of platforms to multiple destinations beyond low earth orbit.

Technologies will provide the capability to utilize and interpret genetic, genomic, proteomic/metabolic, and biophysical data for multigenerational and developmental biological studies.

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Required spaceflight systems and technologies that are subjects of this study include sample handling and management, specimen and sample life support and habitation, sensors and instruments for in-situ bioanalytical and biophysical measurement and control, space biomanufacturing, and sample return capability.

Applicable and Relevant Science Disciplines include: Fundamental Space Biology, Astrobiology and Lunar Science, BioPhysical Sciences, Human Health and Performance and Exploration Life Support, ISS Research, and Planetary Protection.

Targeted Stakeholders and Study Recipients include: OCT, HEOMD, SMD, DoD and other government organizations,
academia, and industry.


1) Define a set of Design Reference Experiments (DREs), which address pertinent space biological science and exploration science questions using model and small organisms;
2) Identify, specify, and recommend the necessary technologies, techniques and systems to accomplish those DREs; and
3) Develop and recommend a strategic technology development and insertion roadmap to provide those technologies for utilization in the BLEO, Moon, Mars and deep space environments in support of Space Biological Research and Human Exploration.

Design Reference Experiment Parameter Selection Matrix

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Study Lead:
Antonio J. Ricco, Ph.D.
Chief Technologist, Small Spacecraft Payloads & Technologies
NASA-Ames Research Center